What You Need to Know About Nano Hemp
Nano Hemp is a new product that has been recently introduced into the cannabis industry. This natural plant contains high amounts of CBD and is being touted as one of the most promising products in the industry. This article outlines some of the most important facts about this product, including its bioavailability, its interactions with the endocannabinoid system, and the potential for its use in cancer treatment.
Nano Water Soluble CBD Technology
CBD, or cannabidiol, is a compound found in hemp. It is believed to be effective in many ways. It may be used for anxiety reduction, anti-inflammatory activity, and beauty enhancement.
It is also said to help with pain relief. It works by stimulating the ECS, or Endocannabinoid System.
CBD's ability to treat cancer is largely dependent on the type of cancer. It has been found to be effective in reducing tumor size, however it is not always effective in preventing or eradicating the cancer.
Several studies have investigated the effects of CBD on cancer cells. Some studies showed that CBD was as effective as THC, while others showed that it was significantly lower. The difference in the effectiveness of CBD and THC depends on the nature of the test conditions.
In a series of experiments, three lung cancer cell lines were compared to THC, and to CBD. The results indicated that the two compounds had similar IC50 values. In five tests, they were even equal.
In another study, CBD was as effective as THC in glioma and neuroblastoma cell xenografts. In these tests, CBD reduced tumor weight by more than 50 mg/kg. The apoptotic effects of CBD and THC depended on the nature of the cancer cells.
Other animal studies have examined the effects of CBD products in breast, prostate, and oesophageal cancer. In these experiments, CBD decreased tumor weight and increased the rate of tumor resection. These findings have not been interpreted in a consistent way.
Although these animal studies are valuable, they have not been able to provide sufficient evidence to determine if CBD has a therapeutic role in treating cancer. As a result, we do not know whether CBD has a role in treating primary tumors.
Bioavailability of Nano Cannabinoids Cannabidiol CBD
The bioavailability of nano hemp is not a topic of interest to most of us. There are some notable exceptions but that does not mean that you should be left out in the cold. After all, the best way to achieve optimal results is to start with a good foundation. One of the first steps in this endeavor is to find the right company.
A top-notch company, such as the fine folks at Nano Hemp Tech Labs, has a number of products and services on tap, including an impressive line of hemp oils, CBD infused lip balms and salves, and topical lotions and ointments.
In Vitro Anticancer Effects
Cannabis sativa, or hemp, is a potent source of biologically active compounds. Its terpenes and cannabinoids show promise for bio-nanotechnology applications. Aside from containing cannabinoids, the plant also boasts a long list of other bioactive substances including vitamins, polyphenols, and amino acids. Its antibacterial and antifungal properties are worthy of mention, and nanoparticles could be the next logical step.
In particular, the molecule that makes the most sense in a nanoparticle is the tetrahydrocannabinol (THC) compound. Its cytotoxic and neuroprotective properties have been lauded in the past, but a potential new application is a plethora of nanoparticles that can deliver a dose of the good stuff to the right patients.
For example, a recent study showed that the in vitro antioxidant effects of D(9)-THC-loaded PLGA nanoparticles were impressive enough to elicit significant cellular responses from LL2 lung tumor bearing immunocompetent C57BL/6 mice. However, it remains to be seen if this is truly a scalable model that can be applied to other types of cancer. The nanoparticles were also found to have improved oral absorption in vivo, thereby enhancing the efficacy of other drugs aimed at delivering the aforementioned chemotherapeutic agents.
The aforementioned FTIR spectra of the nanoparticles in question confirms the claim that hemp, and indeed the whole plant, produces a bevy of functional molecules. Its terpenes and flavonoids show promise in exhibiting anticancer and antifungal effects. Aside from the aforementioned tetrahydrocannabinol, a range of other cannabinoids and terpenes also show promise in this regard. Several of these have been identified in human cell lines.
The most noteworthy among them includes the alkyl-modified phenylethylbenzene derivative methylphenylcyclopropane sulfonate (MCPS), a natural derived phytochemical known to inhibit growth of human breast cancer cell lines in vivo.
Interaction with the Endocannabinoid System
The endocannabinoid system is a lipid signaling system in the brain, which regulates a wide range of physiological processes. It includes two G protein-coupled receptors (CB1 and CB2), endocannabinoids, enzymes for endocannabinoid synthesis and degradation, and several types of neurotransmitter. These components interact with each other to control pain perception, modulate stress, and suppress anxiety.
The endocannabinoid pathway can be targeted by therapeutic agents to improve pain management. However, many of the known therapeutic agents have failed in clinical trials. The reasons for failure include the presence of side effects, variability in clinical populations, and ineffective target engagement.
Recent developments in cannabinoid pharmacology have led to a better understanding of the mechanisms of endocannabinoids. In particular, therapeutic agents targeting the endocannabinoid system have been investigated in preclinical models of pain. These studies show the beneficial effects of cannabinoids in rodents and rats, and suggest a potential role for cannabinoids in the treatment of chronic pain.
Interestingly, cannabinoids produce both aversive and rewarding effects in laboratory animals. Interestingly, the positive reinforcing effects are likely independent of cannabinoid receptor activation, while the negative reinforcing effects are dependent on cannabinoid receptor activation.
In addition to aversive and rewarding effects, cannabinoids have demonstrated antinociceptive and opioid-sparing properties in rodents and humans. A recent systematic review highlighted the need for further studies of the effects of cannabinoids on pain behavior.
The study of the endocannabinoid pathway in rodents and laboratory animals is important for the development of cannabinoid-based therapies for pain. The endocannabinoid signaling system exhibits adaptive changes during pathological conditions. These changes may provide a rationale for targeting the endocannabinoid path in order to reduce nociceptive transmission at all levels of neuroanatomy.
Nano Hemp Tech Labs provide excellent products and services, including hemp oils, CBD lip balms, salves, lotions and ointments.
A recent study showed that PLGA nanoparticles loaded with THC have powerful antioxidant effects in vitro, which elicited significant cellular responses from immune-competent LL2 lung tumor-bearing mice.